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Copy number variation at the GL7 locus contributes to grain size diversity in rice
Yuexing Wang,Guosheng Xiong,Jiang Hu,Liang Jiang,Hong Yu,Jie Xu,Yunxia Fang,Longjun Zeng,Erbo Xu,Jing Xu,Weijun Ye,Xiangbing Meng,Ruifang Liu,Hongqi Chen,Yanhui Jing,Yonghong Wang,Xudong Zhu,Jiayang Li & Qian Qian
NATURE GENETICS
Abstract
Copy number variants (CNVs) are associated with changes in gene expression levels and contribute to various adaptive traits. Here we show that a CNV at the Grain Length on Chromosome 7 (GL7) locus contributes to grain size diversity in rice (Oryza sativa L.). GL7encodes a protein homologous to Arabidopsis thaliana LONGIFOLIA proteins, which regulate longitudinal cell elongation. Tandem duplication of a 17.1-kb segment at the GL7locus leads to upregulation of GL7 and downregulation of its nearby negative regulator, resulting in an increase in grain length and improvement of grain appearance quality. Sequence analysis indicates that allelic variants of GL7 and its negative regulator are associated with grain size diversity and that the CNV at the GL7 locus was selected for and used in breeding. Our work suggests that pyramiding beneficial alleles of GL7 and other yield- and quality-related genes may improve the breeding of elite rice varieties.
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论文编号: |
DOI:10.1038/ng.3346 |
论文题目: |
Copy number variation at the GL7 locus contributes to grain size diversity in rice |
英文论文题目: |
Copy number variation at the GL7 locus contributes to grain size diversity in rice |
第一作者: |
Yuexing Wang,Guosheng Xiong,Jiang Hu,Liang Jiang,Hong Yu,Jie Xu,Yunxia Fang,Longjun Zeng,Erbo Xu,Jing Xu,Weijun Ye,Xiangbing Meng,Ruifang Liu,Hongqi Chen,Yanhui Jing,Yonghong Wang,Xudong Zhu,Jiayang Li & Qian Qian |
英文第一作者: |
Yuexing Wang,Guosheng Xiong,Jiang Hu,Liang Jiang,Hong Yu,Jie Xu,Yunxia Fang,Longjun Zeng,Erbo Xu,Jing Xu,Weijun Ye,Xiangbing Meng,Ruifang Liu,Hongqi Chen,Yanhui Jing,Yonghong Wang,Xudong Zhu,Jiayang Li & Qian Qian |
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2015-07-07 |
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摘要: |
Copy number variants (CNVs) are associated with changes in gene expression levels and contribute to various adaptive traits. Here we show that a CNV at the Grain Length on Chromosome 7 (GL7) locus contributes to grain size diversity in rice (Oryza sativa L.). GL7encodes a protein homologous to Arabidopsis thaliana LONGIFOLIA proteins, which regulate longitudinal cell elongation. Tandem duplication of a 17.1-kb segment at the GL7locus leads to upregulation of GL7 and downregulation of its nearby negative regulator, resulting in an increase in grain length and improvement of grain appearance quality. Sequence analysis indicates that allelic variants of GL7 and its negative regulator are associated with grain size diversity and that the CNV at the GL7 locus was selected for and used in breeding. Our work suggests that pyramiding beneficial alleles of GL7 and other yield- and quality-related genes may improve the breeding of elite rice varieties. |
英文摘要: |
Copy number variants (CNVs) are associated with changes in gene expression levels and contribute to various adaptive traits. Here we show that a CNV at the Grain Length on Chromosome 7 (GL7) locus contributes to grain size diversity in rice (Oryza sativa L.). GL7encodes a protein homologous to Arabidopsis thaliana LONGIFOLIA proteins, which regulate longitudinal cell elongation. Tandem duplication of a 17.1-kb segment at the GL7locus leads to upregulation of GL7 and downregulation of its nearby negative regulator, resulting in an increase in grain length and improvement of grain appearance quality. Sequence analysis indicates that allelic variants of GL7 and its negative regulator are associated with grain size diversity and that the CNV at the GL7 locus was selected for and used in breeding. Our work suggests that pyramiding beneficial alleles of GL7 and other yield- and quality-related genes may improve the breeding of elite rice varieties. |
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NATURE GENETICS |
英文刊物名称: |
NATURE GENETICS |
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其它备注: |
Yuexing Wang,Guosheng Xiong,Jiang Hu,Liang Jiang,Hong Yu,Jie Xu,Yunxia Fang,Longjun Zeng,Erbo Xu,Jing Xu,Weijun Ye,Xiangbing Meng,Ruifang Liu,Hongqi Chen,Yanhui Jing,Yonghong Wang,Xudong Zhu,Jiayang Li & Qian Qian. Copy number variation at the GL7 locus contributes to grain size diversity in rice. NATURE GENETICS. DOI:10.1038/ng.3346 |
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