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Intracellular Temperature Sensing: An Ultra-bright Luminescent Nanothermometer with Non-sensitivity to pH and Ionic Strength
Helin Liu,Yanyan Fan,Jianhai Wang,Zhongsen Song,Hao Shi,Rongcheng Han,Yinlin Sha & Yuqiang Jiang
Scientific Reports
Abstract
Luminescence thermometry usually suffer from cellular complexity of the biochemical environment (such as pH and ionic strength), and thus the accuracy and reliability of the determined intracellular temperature are directly affected. Herein, a photoluminescent nanothermometer composed of polymer encapsulated quantum dots (P-QD) has been developed. And the prepared nanothermometer exhibits some advantages: such as non-sensitivity to pH and ionic strength, as well as high detection sensitivity and ultrahigh reversibility. The intracellular temperature was accurately determined under physiological conditions with different pH and ionic strength, and direct measurement of thermogenesis in individual cells has been achieved.
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论文编号: |
DOI:10.1038/srep14879 |
论文题目: |
Intracellular Temperature Sensing: An Ultra-bright Luminescent Nanothermometer with Non-sensitivity to pH and Ionic Strength |
英文论文题目: |
Intracellular Temperature Sensing: An Ultra-bright Luminescent Nanothermometer with Non-sensitivity to pH and Ionic Strength |
第一作者: |
Helin Liu,Yanyan Fan,Jianhai Wang,Zhongsen Song,Hao Shi,Rongcheng Han,Yinlin Sha & Yuqiang Jiang |
英文第一作者: |
Helin Liu,Yanyan Fan,Jianhai Wang,Zhongsen Song,Hao Shi,Rongcheng Han,Yinlin Sha & Yuqiang Jiang |
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2015-10-12 |
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摘要: |
Luminescence thermometry usually suffer from cellular complexity of the biochemical environment (such as pH and ionic strength), and thus the accuracy and reliability of the determined intracellular temperature are directly affected. Herein, a photoluminescent nanothermometer composed of polymer encapsulated quantum dots (P-QD) has been developed. And the prepared nanothermometer exhibits some advantages: such as non-sensitivity to pH and ionic strength, as well as high detection sensitivity and ultrahigh reversibility. The intracellular temperature was accurately determined under physiological conditions with different pH and ionic strength, and direct measurement of thermogenesis in individual cells has been achieved. |
英文摘要: |
Luminescence thermometry usually suffer from cellular complexity of the biochemical environment (such as pH and ionic strength), and thus the accuracy and reliability of the determined intracellular temperature are directly affected. Herein, a photoluminescent nanothermometer composed of polymer encapsulated quantum dots (P-QD) has been developed. And the prepared nanothermometer exhibits some advantages: such as non-sensitivity to pH and ionic strength, as well as high detection sensitivity and ultrahigh reversibility. The intracellular temperature was accurately determined under physiological conditions with different pH and ionic strength, and direct measurement of thermogenesis in individual cells has been achieved. |
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Scientific Reports |
英文刊物名称: |
Scientific Reports |
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其它备注: |
Helin Liu,Yanyan Fan,Jianhai Wang,Zhongsen Song,Hao Shi,Rongcheng Han,Yinlin Sha & Yuqiang Jiang. Intracellular Temperature Sensing: An Ultra-bright Luminescent Nanothermometer with Non-sensitivity to pH and Ionic Strength. Scientific Reports. DOI:10.1038/srep14879 |
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