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朱立煌


朱立煌,荣誉研究员,博士生导师
 
        1965年毕业于复旦大学生物系遗传专业以来,一直在中国科学院遗传研究所工作。1988年破格晋升为研究员,1996年被国家人事部授予有突出贡献中青年专家称号。1986-1987年比利时根特大学遗传系访问学者,1989— 1992年在美国康乃尔大学植物育种系做客座研究(每年三个月)。曾先后任遗传所学术委员会主任和副所长,中国科学院遗传所、微生物所植物生物技术重点实验室,中国科学院遗传与发育生物学研究所学术委员会主任,植物基因组学国家重点实验室学术委员会主任;也曾任职中国生物工程学会副秘书长,"遗传学报"和"遗传"两刊主编。2008年3月起任荣誉研究员。


        其领导的研究组长期以来一直从事水稻的遗传学和基因组学研究,已在国际SCI刊物上发表论文60篇以上。从2000年起,作为发起人之一与北京基因组研究所等单位一起组织并完成了籼稻93-11基因组的测序,有关论文发表在Science (2002,296:79-92)上,现已成功地克隆了多个水稻重要性状的功能基因。近年来的主要研究领域是与水稻发育和抗病相关的分子遗传学和功能基因组学;通过正向和反向遗传学的途径研究水稻抗病基因的功能及其介导的抗病信号网络,并开展与水稻的花器官分化相关的基因的功能研究。


KEY PUBLICATIONS

Lan Yin, Ying Lan, Lihuang Zhu. Analysis of the protein expression profiling during rice callus differentiation under different plant hormone conditions. Plant Mol Biol. 2008, 68:597–617
 
Dejun Li, Chunhua Yang, Xiaobing Li, Guobiao Ji, Lihuang Zhu. Sense and antisense OsDof12 transcripts in rice. BMC Molecular Biology, 2008, 9:80
 
Xiang T, Zong N, Zou Y, Wu Y, Zhang J, Xing W, Li Y, Tang X, Zhu L, Chai J, Zhou JM. Pseudomonas syringae effector AvrPto blocks innate immunity by targeting receptor kinases. Curr Biol., 2008,18(1):74-80.
 
L. Wan, D,Y. Li, D. L. Zhang, X. Liu, W. J. Fu, L. H. Zhu, M.H. Deng, F.Z. Sun, M.P. Qian.  Conservation and implications of eukaryote transcriptional regulatory regions across multiple soecies. BMC Genomics. 2008, 9: 623
 
Weiman Xing, Yan Zou, Qun Liu, Jianing Liu, Xi Luo, Qingqiu Huang, She Chen, Lihuang Zhu, Ruchang Bi, Quan Hao, Jia-Wei Wu, Jian-Min Zhou & Jijie Chai (2007)The structural basis for activation of plant immunity by bacterial effector protein AvrPto,Nature 449,243-247
 
Yin, L., Tao, Y., Zhao, K., Shao, J., Xu, G., Li, X. , Liu, G., Liu, S., Zhu, L*. (2007) Proteomic and transcriptomic analysis of rice mature seed-derived callus differentiation.  Proteomics 7, 755-768.
 
Junhuang Zou, Shuying Zhang, Weiping Zhang, Gang Li, Zhongxiang Chen, Wenxue Zhai, Xianfeng Zhao, Xuebiao Pan, Lihuang Zhu*. (2006)The rics High-Tillering Dwarf1 encoding an otholog of Arabidopsis MAX3 is requied for negative regulation of outgrowth axillary buds. The Plant Journal 48:687-696.
 
Xuewei Chen, Junjun Shang, DexiChen, CailinLei, YanZou,WenxueZhai,GuozhenLiu, JIchenXu,,ZhongzhuanLing,GangCao,BingtianMa,YupingWang, XianfenZhao,Shigui Li,Lihuang Zhu*. A B-lectin receptor kinase gene conferring rice blast resistance.  The Plant Journal (2006)46: 794-804

Caiyan Chen, Han Xiao, Wenli Zhang, Aiju Wang, Zhihui Xia, Xiaobing Li, Wenxue Zhai, Zhukuan Cheng, Lihuang Zhu*. Adapting rice anther culture to gene transformation and RNA interference. Science in China Series C: Lif Science (2006) 49, 414-428

Jiang Guang Huai, Xia Zhi Hui, Zhou Yong Li, Wan Jia, Li Da Yong, Chen Run Sheng, Zhai Wen Xue and Zhu Li Huang*. Testifying the rice bacterial blight resistance gene xa5 in its function and further analyzing xa5 (Xa5) by comparing with it’s homolog TFIIAγ1. Mol Gen Genomics(2006)275:354-366.
 
Jiabin Tang, Hong’ai Xia, Dayong Li, Mengliang Cao, Wei Tong, Xiuqing Zhang, Songnian Hu, Jian Wang, Jun Yu, Huanming Yang, Lihuang Zhu*     Gene expression profiling in rice young panicle and vegetative organs and identification of  panicle-specofic genes through known gene functions.   Mol Gen Genomics (2005)274:467-476
 
Junhuang Zou, Zengxiang Chen, Shuying Zhang, Weiping Zhang, Guanghuai Jiang, Xingfeng Zhao, Wexue Zhai, Xuebiao Pen, Lihuang Zhu*Characterizations and fine mapping of a mutant gene for high-tillering and dwarf in rice (Oryza sativa L.)Planta (2005)222:604-612
 
Qiong Luo, Kaida Zhou, Xianfeng Zhao, Qianchun Zheng, Hongai Xia, WenxueZhai, Jichen Xu, Xianjun Wu, Hongsong Yang, Lihuang Zhu*  Identification and fine-mapping of a mutant gene for palealess spikelet in rice Planta (2005) 221: 222-230
 
Jiabin Tang, Hongai Xia, Mengliang Cao, Xiuqing Zhang, Wanyong Zeng, Songnian Hu, Wei Tong, Jun Wang, Jun Yu*, Huanming Yang* and Lihuang Zhu*. A comparison of rice Chloroplast Genomes. Plant Physiology (2004) 135:412-420
 
Xianwu Zheng, Xuewei Chen,Xiaohong Zhang, Zhongzhuan Lin, JinjunShang, Jichen Xu, Wenxue Zhai and Lihuang Zhu*. Isolation and identification ofa gene in response torice blast diseasein rice.  Plant Molecular Biology (2004) 54:99-109
 
Ping He, Satya Chintamanani. Zhongying Chen, Lihuang Zhu, Barbara N Kunkel,James R Alfano, Xiaoyan Tang, Jian-Min Zhou*. Activation of a COL1-depedent pathway in Arabdopsis by Pseudomonas syringae type III effectors and coronatine. The plant Journal (2004) 37: 589-602
 
H. Xiao, Y.Wang, D.F.Liu, W.M.Wang, X.B.Li, X.F.Zhao, J.C.Xu, W.X.Zhai, L.H.Zhu*.Functional analysis of the rice AP3 homologue OsMADS16 by RNA interference.  Plant Molecular Biology (2003)52:957-966
 
Yu J, Hu S, Wang J, Wong GK, Li S, Liu B, Deng Y, Dai L, Zhou Y, Zhang X, Cao M, Liu J, Sun J, Tang J, Chen Y, Huang X, Lin W, Ye C, Tong W, Cong L, Geng J, Han Y, Li L, Li W, Hu G, Li J, Liu Z, Qi Q, Li T, Wang X, Lu H, Wu T, Zhu M, Ni P, Han H, Dong W,Ren X, Feng X, Cui P, Li X, Wang H, Xu X, Zhai W, Xu Z, Zhang J, He S, Xu J, Zhang K, Zheng X, Dong J, Zeng W, Tao L, Ye J, Tan J,Chen X, He J, Liu D, Tian W, Tian C, Xia H, Bao Q, Li G, Gao H, Cao T, Zhao W, Li P, Chen W, Zhang Y, Hu J, Liu S, Yang J, Zhang G,Xiong Y, Li Z, Mao L, Zhou C, Zhu Z, Chen R, Hao B, Zheng W, Chen S, Guo W, Tao M, Zhu L*., Yuan L*., Yang H*.A draft sequence of the rice genome (Ozyza sativa L.ssp. in dica) Science (2002) 296:79-92
 
Cheng Z.K, Yan,,H.H, Yu,H.X, Tang,S.C, Jing,J.M,Gu,M.H.,and Zhu,L.H*. Development and application of a complete set of rice telotrisomis. Genetics(2001)157∶361-368
 
Wang.W.M., Zhai.W.X., Luo.M.Z., Jiang.G.H., Chen.X.W., Li.X.B., Wing.R.A. and Zhu.L.H*. Chromosome Landing at the bacterial blight Resistance Gene Xa4 locus Using a deep coverage vice BAC library. MGG(2001)265∶118-125