李家洋，男，博士，中国科学院院士，美国科学院外籍院士，研究员，博士生导师
1956年7月出生于安徽肥西，植物分子遗传学家。1982年初获安徽农业大学学士学位，1984年获中科院遗传研究所硕士学位，1991年获美国布兰代斯大学博士学位，并进入美国康乃尔大学汤普逊植物研究所从事博士后研究。1994年回国工作，历任中国科学院遗传研究所所长助理、所长，遗传与发育生物学研究所所长。2004年1月任中国科学院党组成员、副院长，2011年10月任农业部副部长、党组成员、中国农业科学院院长。
先后获“国家杰出青年基金”、中国科学院“百人计划”、国家自然科学委员会优秀团队研究基金。2004年获全球华人生物科学家大会生命科学成就奖和何梁何利生命科学奖，2005年获国家自然科学奖二等奖、发展中国家科学院讲演奖、长江学者成就二等奖，2011年获美国植物生物学家协会（American Society of Plant Biologists) 终身会员奖（Corresponding Membership Award）。2001年当选中国科学院院士，2004年当选发展中国家科学院院士，2011年当选美国科学院外籍院士。
研究方向为高等植物生长发育与代谢的分子遗传学，以粮食作物水稻和模式植物拟南芥为材料，研究植物激素（Auxin和Strigolactones）的合成途径与作用机理，着重于阐明高等植物株型形成的分子机理，并致力于水稻的分子品种设计，培育高产、优质、高抗、高效新品种。
Recent Major Publications
1. Li J, Chua N. (2010) A comprehensive understanding of plant growth and development. Curr Opin Plant Biol doi:10.1016/j.pbi.2010.11.003
2. Wang Y, Li J. (2010) Branching in rice. Curr Opin Plant Biol, doi:10.1016/ j.pbi.2010.11.002
3. Huang X, Wei X, Sang T, Zhao Q, Feng Q, Zhao Y, Li C, Zhu C, Lu T, Zhang Z, Li M, Fan D, Guo Y, Wang A, Wang L, Deng L, Li W, Lu Y, Weng Q, Liu K, Huang T, Zhou T, Jing Y, Li W, Lin Z, Buckler E, Qian Q, Zhang Q, Li J and Han B (2010) Genome-wide association studies of 14 agronomic traits in rice landraces. Nature Genet 42, 961-967. (Commentary in News and Views: Nature Genet 42, 926-927)
4. Xiong G, Li R, Qian Q, Song X, Liu X, Yu Y, Zeng D, Wan J, Li J and Zhou Y (2010) The rice dynamin-related protein DRP2B mediates membrane trafficking, and thereby plays a critical role in secondary cell wall cellulose biosynthesis. Plant J 64, 56-70.
5. Jiao Y, Wang Y, Xue D, Wang J, Yan M, Liu G, Dong G, Zeng D, Lu Z, Zhu X, Qian Q and Li J (2010) Regulation of OsSPL14 by OsmiR156 defines ideal plant architecture in rice.Nature Genet 42: 541-544.(Commentary in News and Views: Nature Genet 42, 475-476)
6. Zhang M, Zhang B, Qian Q, Yu Y, Li R, Zhang J, Liu X, Zeng D, Li J and Zhou Y (2010) Brittle Culm12, a dual-targeting Kinesin-4 protein, controls cell cycle progression and wall properties in rice.Plant J 63, 312-328.
7. Cui X, Ge C, Wang R, Wang H, Chen W, Fu Z, Jiang X, Li J and Wang Y (2010) The BUD2 mutation affects plant architecture through altering response to cytokinin and auxin in Arabidopsis.Cell Res 20:576-586.
8. Wang H, Zhu Y, Fujioka S, Asami T, Li J and Li JM (2009) Regulation of Arabidopsis brassinosteroid signaling by atypical basic helix-loop-helix proteins. Plant Cell21: 3781-3791.
9. Tian Z, Qian Q, Liu Q, Yan M, Liu X, Yan C, Liu G, Gao Z, Tang S, Zeng D, Wang Y, Yu J, Gu M and Li J (2009) Allelic diversities in rice starch biosynthesis lead to a diverse array of rice eating and cooking qualities. Proc Natl Acad Sci USA 106: 21760–21765.
10. Melcher K, Ng L-M, Zhou X, Soon F-F, Xu Y, Suino-Powell K, Park S-Y, Weiner J, Fujii H, Chinnusamy V, Kovach A, Li J, Wang Y, Li J, Peterson F, Jensen D, Yong E-L, Volkman B, Cutler S, Zhu J-K and Xu HE. A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors. Nature 462: 602-610.
11. Lin H, Wang R, Qian Q, Yan M, Meng X, Fu Z, Yan C, Jiang B, Su Z, Li J, and Wang Y (2009) DWARF27, an iron-containing protein required for the biosynthesis of strigolactones, regulates rice tiller bud outgrowth. Plant Cell 21: 1512-1525.
12. Huang X, Qian Q, Liu Z, Sun H, He S, Luo D, Xia G, Chu C, Li J and Fu X (2009). Natural variation at the DEP1 locus enhances grain yield in rice. Nature Genet 41: 494-497.
13. Li S, Qian Q, Fu Z, Zeng D, Meng X, Kyozuka J, Maekawa M, Zhu X, Zhang J, Li J and Wang Y (2009) Short panicle1 encodes a putative PTR transporter and determines rice panicle size. Plant J 58: 592-605.
14. Zhou Y, Li S, Qian Q, Zeng D, Zhang M, Guo L, Liu XL, Zhang B, Deng L, Liu X, Luo G, Wang X and Li J (2009) BC10, a DUF266-containing and golgi-located type II membrane protein, is required for cell wall biosynthesis in rice (Oryza sativa L.)Plant J 57: 446-462.
15. Yu Y, Tang T, Qian Q, Wang Y, Yan M, Zeng D, Han B, Wu Chung-I, Shi S and Li J (2008) Independent losses of function in a polyphenol oxidase in rice: differentiation in grain discoloration between subspecies and the role of positive selection under domestication. Plant Cell 20: 2946-2959.
16. Wang Y and Li J(2008) Rice, rising.Nature Genet 40: 1273-1275.
17. Wang Y and Li J (2008) Molecular basis of plant architecture.Annu Rev Plant Biol 59: 253-279.
18. Xu W, Huang J, Li B, Li J and Wang Y (2008) Is kinase activity essential for biological functions of BRI1? Cell Res 18: 472-478.
19. Li P, Wang Y, Qian Q, Fu Z, Wang M, Zeng D, Li B, Wang X, and Li J ( (2007) LAZY1controls rice shoot gravitropism through regulating polar auxin transport. Cell Res 17: 402-410 (Cover story).
20. Yu B, Lin Z, Li H, Li X, Li J, Wang Y, Zhang X, Zhu Z, Zhai W, Wang X, Xie D and Sun C (2007) TAC1, a major quantitative trait locus controlling tiller angle in rice. Plant J 52:891-898
21. Wang Y, Chen M and Li J (2007) Rice. In Biotechnology in Agriculture and Forestry, Vol. 59 Transgenic Crops IV (By E.C Pua and M.R Davey), Springer-Verlag Berlin Heidelberg. Pp. 35-54.
22. Zeng D, Yan M, Wang Y, Liu X, Qian Q and Li J (2007) Du1, encoding a novel Prp1 protein, regulates starch biosynthesis through affecting the splicing of Wxbpre-mRNAs in rice (Oryza sativa L.) Plant MolBiol 65: 501–509.
23. Dai Y, Wang H, Li B, Huang J, Liu X, Zhou Y, Mou Z, Li J (2006) Increased Expression of MAPKK7 causes deficiency in polar auxin transport and leads to plant architectural abnormality in Arabidopsis. Plant Cell 18: 308-320.
24. Wang Y and Li J (2006) Genes controlling plant architecture.Curr Opin Biotechnol 17: 123-129.
25. Xiong G, Hu X, Jiao Y, Yu Y, Chu C, Li J, Qian Q and Wang Y (2006) LEAFY HEAD2, which encodes a putative RNA-binding protein, regulates shoot development of rice. Cell Res 16: 267-276 (Cover story).
26. Ge C, Cui X, Wang Y, Hu Y, Fu Z, Zhang D, Cheng Z, and Li J (2006) BUD2, encoding an S-adenosylmethionine decarboxylase, is required for Arabidopsis growth and development. Cell Res 16: 446-456 (Cover story).
27. Wang Y, Xue Y and Li J (2005) Towards molecular breeding and improvement of rice in China. Trends Plant Sci 10: 610-61.
28. Wang Y and Li J (2005) The plant architecture of rice (Oryza sativa L.). Plant Mol Biol 59: 75-84.
29. Hu Y, Wang Y, Liu X and Li J (2004) ArabidopsisRVA1 is down-regulated by brassinosteroid and may act as a negative regulator during plant development. Cell Res 14: 8-15.
30. Li Y, Qian Q, Zhou Y, Yan M, Sun L, Zhang M, Fu Z, Wang Y, Han B, Pang X, Chen M and Li J (2003) BRITTLE CULM 1, which encodes a COBRA-like protein, affects the mechanical properties of rice plants. Plant Cell 15: 2020-2031 (Cover story).
31. Li X, Qian Q, Fu Z, Wang Y, Xiong G, Zeng D, Wang X, Liu X, Teng S, Hiroshi F, Yuan M, Luo D, Han B, Li J (2003) Control of tillering in rice. Nature 422: 618-621.
32. Mou Z, Wang X, Dai Y, Bao F, Han C, Ouyang J, Hu Y, Fu F and Li J (2002) Silencing of phosphoethanolamine N-methyltransferase results in temperature-sensitive male sterility and salt hypersensitivity in Arabidopsis. Plant Cell 14: 2031-2043.
33. Feng Q, et al. (2002) Sequence and analysis of rice chromosome 4. Nature 420: 336-340 (Cover story).
34. Hu Y, Bao F and Li J (2000) The promotive effect of brassinosteroids on cell division involves a distinct CycD3-induction pathway in Arabidopsis. Plant J 24: 693-701.
35. Ouyang J, Shao X and Li J (2000) Indole-3-glycerol phosphate, a branchpoint of indole-3-acetic acid biosynthesis from tryptophan biosynthetic pathway in Arabidopsis thaliana. Plant J 24: 327-333.
36. Mou Z, He Y, Dai Y, Liu X and Li J (2000) Deficiency in fatty acid synthase leads to premature cell death and dramatic alterations in plant morphology. Plant Cell 12: 405-417. |
