1996年和1999年中国农业大学获得硕士和博士学位，1999年至2004年在瑞士ETH Zurich和美国Hawaii Agriculture Research Center进行博士后研究，2004年回国到中国农业大学工作并获得国家杰出青年基金，2016年到中国科学院遗传与发育生物学研究所工作担任课题组长。
小麦锈病（条锈病、叶锈病）、白粉病和叶枯病是严重危害小麦生产的重要病害。课题组收集国内外的小麦野生种、地方品种和育成品种，进行系统的抗病性鉴定和遗传分析，利用分子标记定位种质资源中的抗病基因。利用比较基因组学手段，应用高通量SNP分析和下一代测序手段对抗病基因进行精细定位和图位克隆，旨在解析小麦对重要真菌性病害的抗性遗传和分子机理，研究小麦抗病基因的遗传进化和变异机制，开发抗病基因功能标记应用于小麦分子育种。
小麦产量构成因素、株型（株高、叶片形态、茎杆质地等）和抗逆性（根系性状）是影响小麦产量的重要农艺性状。课题组以小麦遗传群体和自然群体为材料，利用高通量SNP分析和下一代测序技术进行遗传作图，对控制重要农艺性状的基因/QTL进行定位、精细定位和图位克隆，应用于小麦产量潜力的遗传改良和分子育种。
主要论文：（*通讯作者）
Xiaocui Yan#, Miaomiao Li#, Peipei Zhang#, Guihong Yin#, Huaizhi Zhang, Takele Weldu Gebrewahid, Jianping Zhang, Lingli Dong, Daqun Liu, Zhiyong Liu*, Zafeng Li* (2021) High-temperature wheat leaf rust resistance gene Lr13 exhibits pleiotropic effects on hybrid necrosis. Molecular Plant, 14:1029-1032
Qiuhong Wu#, Fei Zhao#, Yongxing Chen, Panpan Zhang, Huaizhi Zhang, Guanghao Guo, Jingzhong Xie, Lingli Dong, Ping Lu, Miaomiao Li, Shengwei Ma, Tzion Fahima, Eviatar Nevo, Hongjie Li, Yijing Zhang*, Zhiyong Liu* (2021) Bulked segregant CGT-Seq-facilitated map-based cloning of a powdery mildew resistance gene originating from wild emmer wheat (Triticum dicoccoides). Plant Biotechnology Journal, 19:1288-1290
Yahui Li, Ruiming Lin, Jinhuang, Xiaohan Shi, Dan Qiu, Peipei Wu, Gebremedhin Habteab Goitom, Siqi Wang, Hongjun Zhang, Li Yang, Hongwei Liu, Qiuhong Wu, Jingzhong Xie, Yang Zhou,
Zhiyong Liu*, Hongjie Li* (2021) Mapping of stripe rust resistance gene
Yr041133 by BSR-Seq analysis. The Crop Journal,
https://doi.org/10.1016/j.cj.2021.06.009
Junhua Peng*, Zhiyong Liu*, Xionglun Liu*, Jun Yan, Dongfa Sun, Eviatar Nevo (2021) Evolutionary agriculture domestication of wild emmer wheat. In Solomon P. Wasser and Milana Frenkel-Morgenstern edited: New Horizons in Evolution. Academic Press, Elsevier, pp193-255 DOI:10.1016/B978-0-323-90752-1.00007-9
Peipei Wu, Li Yang, Guanghao Guo, Jinghuang Hu, Dan Qiu, Yahui Li, Xiaohan Shi, Hongjun Zhang, Hongwei Liu, Juntao Zhao, Guozhong Sun, Yang Zhou, Zhiyong Liu*, Hongjie Li* (2021) Molecular mapping and identification of a candidate gene for new locus Hg2 conferring hairy glume in wheat. Plant Science, 307:110879
Miaomiao Li, Lingli Dong*, Beibei Li, Zhengzhong Wang, Jingzhong Xie, Dan Qiu, Yahui Li, Wenqi Shi, Lijun Yang, Qiuhong Wu, Yongxing Chen, Ping Lu, Guanghao Guo, Huaizhi Zhang, Panpan Zhang, Keyu Zhu, Yiwen Li, Yan Zhang, Rongge Wang, Chengguo Yuan, Wei Liu, Dazhao Yu, Ming-Cheng Luo, Tzion Fahima, Eviatar Nevo, Hongjie Li*, Zhiyong Liu* (2020) A CNL protein in wild emmer wheat confers powdery mildew resistance. New Phytologist, 228:1027-1037
Jingzhong Xie#, Guanghao Guo#, Yong Wang#, Tiezhu Hu#, Lili Wang, Jingting Li, Dan Qiu, Yahui Li, Qiuhong Wu, Ping Lu, Yongxing Chen, Lingli Dong, Miaomiao Li, Huaizhi Zhang, Panpan Zhang, Keyu Zhu, Beibei Li, Karin R. Deal, Naxin Huo, Yan Zhang, Ming-Cheng Luo, Sanzhen Liu, Yong Qiang Gu*, Hongjie Li*, Zhiyong Liu* (2020) A rare single nucleotide variant in Pm5e confers powdery mildew resistance in common wheat. New Phytologist, 228:1011-1026
Ping Lu, Li Guo, Zhenzhong Wang, Beibei Li1, Jing Li, Yahui Li, Dan Qiu, Wenqi Shi, Lijun Yang, Ning Wang, Guanghao Guo, Jingzhong Xie, Qiuhong Wu, Yongxing Chen, Miaomiao Li, Huaizhi Zhang, Lingli Dong, Panpan Zhang, Keyu Zhu, Dazhao Yu, Yan Zhang, Karin R. Deal, Naxin Huo, Cuimin Liu, Ming-Cheng Luo, Jan Dvorak, Yong Qiang Gu, Hongjie Li*, Zhiyong Liu* (2020) A rare gain of function in a wheat tandem kinase confers resistance to powdery mildew. Nature Communications, 11:680
Panpan Zhang, Guanghao Guo, Qiuhong Wu, Yongxing Chen, Jingzhong Xie, Ping Lu, Beibei Li, Lingli Dong, Miaomiao Li, Rongge Wang, Chengguo Yuan, Huaizhi Zhang, Keyu Zhu, Wenling Li, Zhiyong Liu* (2020) Identification and fine mapping of spot blotch (Bipolaris sorokiniana) resistance gene Sb4 in wheat. Theor Appl Genet, 133:2451–2459
Qiuhong Wu, Yongxing Chen, Jingzhong Xie, Lingli Dong, Zhenzhong Wang, Ping Lu, Rongge Wang, Chengguo Yuan, Yan Zhang, Zhiyong Liu* (2021) A 36 Mb terminal deletion of chromosome 2BL is responsible for a wheat semi-dwarf mutation. The Crop Journal 9:873-881
Jian Yang, Yanjie Zhou, Weiguo Hu, Yu’e Zhang, Yong Zhou, Yongxing Chen, Xicheng Wang, Hong Zhao, Tingjie Cao* and Zhiyong Liu* (2020) Unlocking the relationships among population structure, plant architecture, growing season, and environmental adaptation in Henan wheat cultivars. BMC Plant Biology 20:469
Yahui Li, Xiaohan Shi, Jinghuang Hu, Peipei Wu, Dan Qiu, Yunfeng Qu, Jingzhong Xie, Qiuhong Wu, Hongjun Zhang, Li Yang, Hongwei Liu, Yang Zhou, Zhiyong Liu*, and Hongjie Li* (2020) Identification of a recessive gene PmQ conferring resistance to powdery mildew in wheat landrace Qingxinmai using BSR-Seq analysis. Plant Disease, 104:743–751
Jian Yang, Yanjie Zhou, Yu’e Zhang, Weiguo Hu, Qiuhong Wu, Yongxing Chen, Xicheng Wang, Guanghao Guo, Zhiyong Liu*, Tingjie Cao* and Hong Zhao (2019) Cloning, characterization of TaGS3 and identification of allelic variation associated with kernel traits in wheat (Triticum aestivum L.). BMC Genetics, 20:98
Lei Cui, Dan Qiu, Lei Sun, Yu Sun, Yongkang Ren, Hongjun Zhang, Jingting Li, Jingwei Zou, Peipei Wu, Jinghuang Hu, Jingzhong Xie, Hongwei Liu, Li Yang, Yang Zhou, Yan Lv, Zhiyong Liu*, T.D. Murray*, Hongjie Li* (2020) Resistance to Heterodera filipjevi and H. avenae in winter wheat is conferred by different QTL. Phytopathology, 100:472-482
Yueqiang Zhang, Zhong Wang, Zheru Fan, Jianfeng Li, Xin Gao, Hongzhi Zhang, Qi Zhao, Zhaoying Wang, Zhiyong Liu* (2019) Phenotyping and evaluation of CIMMYT WPHYSGP nursery lines and local wheat varieties under two irrigation regimes. Breeding Science, 69:55-67
Jian Yang, Yanjie Zhou, Qiuhong Wu, Yongxing Chen, Panpan Zhang, Yu'e Zhang, Weiguo Hu, Xicheng Wang, Hong Zhao, Lingli Dong, Jun Han, Zhiyong Liu*, Tingjie Cao*. (2019) Molecular characterization of a novel TaGL3-5A allele and its association with grain length in wheat (Triticum aestivum L.). Theor Appl Genet, 132:1799-1814
Deyun Zhang, Keyun Zhu, Lingli Dong, Yong Liang, Genqiao Li, Tilin Fang, Guanghao Guo, Qiuhong Wu, Jingzhong Xie, Yongxing Chen, Ping Lu, Miaomiao Li, Huaizhi Zhang, Zhenzhong Wang, Yan Zhang, Qixin Sun, Zhiyong Liu* (2019) Wheat powdery mildew resistance gene Pm64 derived from wild emmer (Triticum turgdium var. dicoccoides) is tightly linked in repulsion with stripe rust resistance gene Yr5. The Crop Journal, 7:761-770
Jinghuang Hu, Jingting Li*, PeipeiWu, Yahui Li, Dan Qiu, Yunfeng Qu, Jingzhong Xie, Hongjun Zhang, Li Yang, Tiantian Fu, Yawei Yu, Mengjuan Li, Hongwei Liu, Tongquan Zhu, Yang Zhou, Zhiyong Liu*, and Hongjie Li* (2019) Development of SNP, KASP, and SSR markers by BSR-Seq technology for saturation of genetic linkage map and efficient detection of wheat powdery mildew resistance gene Pm61. International Journal of Molecular Science, 20:750
Peipei Wu. Jinghuang Hu, Jingwei Zou, Dan Qiu, Yunfeng Qu, Yahui Li, Teng Li, Hongjun Zhang, Li Yang, Hongwei Liu, Yang Zhou, Zhongjun Zhang, Jingting Li*, Zhiyong Liu*, Hongjie Li* (2019) Fine mapping of the wheat powdery mildew resistance gene Pm52 using comparative genomics analysis and the Chinese Spring reference genomic sequence. Theor Appl Genet, 132:1451–1461
Huigai Sun, Jinghuang Hu, Wei Song, Dan Qiu, Lei Cui, Peipei Wu, Hongjun Zhang, Hongwei Liu, Li Yang, Yunfeng Qu, Yahui Li, Teng Li, Wei Cheng, Yang Zhou, Zhiyong Liu*, Jingting Li*, Hongjie Li* (2018) Pm61: a recessive gene for resistance to powdery mildew in wheat landrace Xuxusanyuehuang identified by comparative genomics analysis. Theoretical and Applied Genetics, 131:2085-2097
Miaomiao Li, Beibei Li, Guanghao Guo, Yongxing Chen, Jingzhong Xie, Ping Lu, Qiuhong Wu, Deyun Zhang, Huaizhi Zhang, Jian Yang, Panpan Zhang, Yan Zhang, Zhiyong Liu* (2018) Mapping a leaf senescence gene els1 by BSR-Seq in common wheat. The Crop Journal, 6:236-243
Yong Wang, Huaizhi Zhang, Jingzhong Xie, Bingmin Guo, Yongxing Chen, Huaiyu Zhang, Ping Lu, Qiuhong Wu, Miaomiao Li, Deyun Zhang, Guanghao Guo, Jian Yang, Panpan Zhang, Yan Zhang, Xicheng Wang, Hong Zhao, Tingjie Cao*, Zhiyong Liu* (2018) Mapping stripe rust resistance genes by BSR-Seq: YrMM58 and YrHY1 on chromosome 2AS in Chinese wheat lines Mengmai 58 and Huaiyang 1 are Yr17. The Crop Journal, 6:91-98
Zhenzhong Wang, Jingzhong Xie, Li Guo, Deyun Zhang, Genqiao Li, Tilin Fang, Yongxing Chen, Jun Li, Qiuhong Wu, Ping Lu, Miaomiao Li, Haibin Wu, Huaizhi Zhang, Yan Zhang, Wuyun Yang, Mingcheng Luo, Tzion Fahima, Zhiyong Liu* (2018) Molecular mapping of YrTZ2, a stripe rust resistance gene in wild emmer accession TZ-2 and its comparative analyses with Aegilops tauschii. Journal of Integrative Agriculture, 17:1267-1275
Yong Wang, Jingzhong Xie, Huaizhi Zhang, Bingmin Guo, Shunzong Ning, Yongxing Chen, Ping Lu, Qiuhong Wu, Miaomiao Li, Deyun Zhang, Guanghao Guo, Yan Zhang, Dengcai Liu, Shaokui Zou, Jianwei Tang, Hong Zhao, Xicheng Wang, Jun Li, Wuyun Yang, Tingjie Cao*, Guihong Yin*, Zhiyong Liu* (2017) Mapping stripe rust resistance gene YrZH22 in Chinese wheat cultivar Zhoumai 22 by bulked segregant RNA-Seq (BSR-Seq) and comparative genomics analyses. Theor Appl Genet, 130:2191-2201
Guoxin Wang, Ling Wang, Yu Cui, Meihua Yu, Chen Dang, Hao Wang, Xuejiao Jin, Lijie Yan, Qiuhong Wu, Dawei Li, Zhiyong Liu* (2017) RNA-seq analysis of Brachypodium distachyon responses to Barley stripe mosaic virus infection. The Crop Journal, 5:1-10 (Cover story)
Jingzhong Xie, Lili Wang, Yong Wang, Huaizhi Zhang, Shenghui Zhou, Qiuhong Wu, Yongxing Chen, Zhenzhong Wang, Guoxin Wang, Deyun Zhang, Yan Zhang, Tiezhu Hu*, Zhiyong Liu* (2017) Fine mapping of powdery mildew resistance gene PmTm4 in wheat using comparative genomics. Journal of Integrative Agriculture, 16:540-550
Sheng-hui Zhou, Lin Fu, Qiu-hong Wu, Jiao-jiao Chen, Yong-xing Chen, Jing-zhong Xie, Zhen-zhong Wang, Guo-xin Wang, De-yun Zhang, Yong Liang, Yan Zhang, Ming-shan You, Rong-qi Liang, Jun Han, Zhiyong Liu* (2017) QTL mapping revealed TaVp-1A conferred pre-harvest sprouting resistance in wheat population Yanda 1817×Beinong 6. Journal of Integrative Agriculture, 16:435-444
Jingzhong Xie, Naxin Huo, Shenghui Zhou, Yi Wang, Guanghao Guo, Karin R. Deal, Shuhong Ouyang, Yong Liang, Zhenzhong Wang, Lichan Xiao, Tingting Zhu, Tiezhu Hu, Vijay Tiwari, Jianwei Zhang, Hongxia Li, Zhongfu Ni, Yingyin Yao, Huiru Peng, Shengli Zhang, Olin D. Anderson, Patrick E. McGuire, Jan Dvorak*, Ming-Cheng Luo*, Zhiyong Liu*, Yong Q. Gu*, Qixin Sun* (2017) Sequencing and comparative analysis of Aegilops tauschii chromosome arm 3DS revealed rapid evolution of Triticeae genomes. Journal of Genetics Genomics, 44:51-61
