2006年上海交通大学学士，2012年中国科学院植物研究所博士。2013-2018年美国宾夕法尼亚大学生物系博士后。2018年6月任中国科学院遗传与发育生物学研究所研究员，博士生导师；2019年4月兼任CEPAMS（中科院-英国John Innes Centre联合中心）课题组长；2021年3月入选Faculty 1000组织。
植物生长发育受到内在的遗传程序调控及所处的外部环境影响，内外因素如何协同调控发育是重要的生物学问题。同时，作物产量受到环境因素的严重制约。课题组以小麦及拟南芥为研究材料，研究表观遗传调控开花转变，果实发育以及对环境因子变换（水分和温度）的适应性。研究将结合表观遗传组学、转录组学，正向遗传突变体库筛选以及反向基因功能分析，利用高通量测序，遗传、生化、分子、细胞生物学等技术手段来解析具体的分子机制。
代表论著：
近期发表论文（*共通讯作者；#共第一作者）：
2022
1.Shengnan Li#, Dexing Lin#, Yunwei Zhang#, Min Deng#, Yongxing Chen, Bin Lv, Boshu Li, Yuan Lei, Yanpeng Wang, Long Zhao, Yueting Liang. Jinxing Liu, Kunling Chen, Zhiyong Liu, Jun Xiao*, Jinlong Qiu*, Caixia Gao*. Genome edited powdery mildew resistance in wheat without growth penalties, Nature. In press
2.Un-Sa Lee, Tomasz Bieluszewski, Jun Xiao, Ayako Yamaguchi, Doris Wanger. (2022) H2A.Z contributes to Trithorax activity at the AGAMOUS locus. Molecular Plant.
2021
3.Tomasz Bieluszewski#, Jun Xiao#, Yiman Yang, Doris Wagner. (2021) PRC2 activity, recruitment, and silencing: a comparative perspective. Trends in Plant Science 19:S1360-1385(21)00148-5. doi: 10.1016/j.tplants.2021.06.006.
4.Yanmei Chen, Jun Xiao, Peng Liu. (2021) Dissecting the plant chromatin interactome using mass spectrometry. Trends in Biotechnology. 29:S0167-7799(21)00132-3. doi: 10.1016/j.tibtech.2021.06.002.
5.Shujuan Xu, Qi Dong, Min Deng, Dexing Lin, Jun Xiao, Peilei Cheng, Lijing Xing, Yuda Niu, Caixia Gao, Wenhao Zhang, Yunyuan Xu, Kang Chong.(2021) The vernalization-induced long non-coding RNA VAS functions with the transcription factor TaRF2b to promote TaVRN1 expression for flowering in hexaploid wheat. Molecular Plant. 14(9):1525-1538. doi: 10.1016/j.molp.2021.05.026.
6.Run Jin*, Samantha Klasfeld*, Yang Zhu, Meilin Fernandez Garcia, Jun Xiao, Soon-Ki Han, Adam Konko, Doris Wagner. (2021) LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate. Nature Communications, 12(1):626. doi: 10.1038/s41467-020-20883-w.
2019
7.Bo Sun, Yingying Zhou, Jie Cai, Erlei Shang, Nobutoshi Yamaguchi,
Jun Xiao, Liang-Sheng Looi, Wan-Yi Wee, Xiuying Gao, Doris Wagner, Toshiro Ito. (2019) Integration of transcriptional repression and Polycomb-mediated silencing of WUSCHEL in floral meristems.
Plant Cell. DOI:
https://doi.org/10.1105/tpc.18.00450.
8.Shujuan Xu,
Jun Xiao, Fang Yin, Xiaoyu Guo, Lijing Xing, Yunyuan Xu, Kang Chong. (2019) The protein modifications of O-GlcNAcylation and phosphorylation mediate vernalization response for flowering in winter wheat.
Plant Physiology. DOI:
https://doi.org/10.1104/pp.19.00081.
2018
9.Lijing Xing, Yan Liu, Shujuan Xu, Jun Xiao, Bo Wang, Hanwen Deng, Zhuang Lu, Yunyuan Xu, Kang Chong. (2018) Arabidopsis O-GlcNAc transferase SEC actives histone methyltransferase ATX1 to regulate flowering. EMBO Journal, doi:10.15252/embj.201798115.
2017及以前
1.Xiao J, Jin R, Yu X, Shen M, Wagner J, Pai A, Song C, Zhuang M, Kelasfeld S, He CS, Santos AM, Helliwell C, Pruneda-Paz J, Kay S, Lin XW, Cui SJ, Fernandez M, Clarenz O, Goodrich J, Zhang XY, Austin R, Bonasio R, Wagner D. (2017) Cis- and trans-determinants of Polycomb Repressive Complex 2 recruitment in Arabidopsis. Nature Genetics, doi:10.1038/ng.3937 (Nature Genetic news and views highlight, F1000 Prime)
2.
Xiao J, Xu S, Li C, Xu Y, Xing L, Niu Y, Huan Q, Tang Y, Zhao C, Wagner D, Gao C, Chong K. (2014)
O-GlcNAc-mediated interaction between VER2 and TaGRP2 elicits TaVRN1 mRNA accumulation during vernalization in winter wheat.
Nature Communications 5:4572. (
F1000 Prime)
3.Wu MF#, Yamaguchi N#, Xiao J#, Bargmann B, Estelle M, Sang Y, Wagner D. (2015) An auxin-regulated chromatin state switch directs organogenesis in Arabidopsis. eLife 4:e09269. (Co-first author, F1000 Prime)
4.Xiao J#, Jin R#, Wagner D. (2017) Developmental transitions: integrating environmental cues with hormonal signaling in the chromatin landscape. Genome Biology, 18 (1):88.
6.Xiao J#, Li CH#, Xu SJ, Xing LJ, Xu YY, Chong K. (2015) AtJAC1 Regulates Nuclear Accumulation of GRP7, influencing RNA processing of FLC antisense transcripts and flowering time in Arabidopsis. Plant Physiol 169 (3):2102-2117.
7.Xiao J, Lee US, Wagner D. (2016) Tug of war: adding and removing histone lysine methylation in Arabidopsis. Curr Opin Plant Biol 4:41-53.
8.Xiao J#, Zhang H#, Xing LJ, Xu SJ, Liu HH, Chong K, Xu YY. (2013) Requirement of histone acetyltransferases HAM1/2 for epigenetic modification of FLC to regulate flowering in Arabidopsis. J Plant Physiol 170(4):444-451.
9.
Ma Y,
Dai X,
Xu Y,
Luo W,
Zheng X,
Zeng D,
Pan Y,
Lin X,
Liu H,
Zhang D,
Xiao J,
Guo X,
Xu S,
Niu Y,
Jin J,
Zhang H,
Xu X,
Li L,
Wang W,
Qian Q,
Ge S,
Chong K. (2015) COLD1 Confers Chilling Tolerance in Rice.
Cell 160(6):1209-1221. (
F1000 Prime, Cover story)
10.Bossi F, Fan J, Xiao J, Chandra L, Shen M, Wagner D, Rhee SY. (2017) Systematic discovery of novel eukaryotic transcriptional regulators using non-sequence homology based prediction. BMC Genomics, 18:480 DOI: 10.1186/s12864-017-3853-9
11.Liu YJ, Xu YY, Xiao J, Ma QB, Li D, Xue Z, Chong K. (2011) OsDOG, a gibberellin-induced A20/AN1 zinc-finger protein, negatively regulates gibberellin-mediated cell elongation in rice. J Plant Physiol 168(10):1098-1105.
12.Li J, Jiang JF, Qian Q, Xu YY, Zhang C, Xiao J, Du C, Luo W, Zou GX, Chen ML, Huang YQ, Feng YQ, Cheng ZK, Yuan M, Chong K. (2011) Mutation of Rice BC12/GDD1, Which Encodes a Kinesin-Like Protein That Binds to a GA Biosynthesis Gene Promoter, Leads to Dwarfism with Impaired Cell Elongation. Plant Cell 23(2):628-640.
13.Ma QB, Dai XY, Xu YY, Guo J, Liu YJ, Chen N, Xiao J, Zhang DJ, Xu ZH, Zhang XS* and Chong K*. (2009) Enhanced tolerance to chilling stress in OsMYB3R-2 transgenic rice is mediated by alteration in cell cycle and ectopic expression of stress genes. Plant Physiol 150: 244-256.
