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肖军


肖军,博士,研究员,博士生导师
        2006年本科毕业于上海交通大学生物技术专业,2012年在中科院植物研究所获得发育生物学博士学位,2013年加入美国宾夕法尼亚大学从事博士后研究。2018年入选中组部第十四批“千人计划”青年项目并于2018年6月加入中科院遗传与发育研究所。
 
        本人长期从事表观遗传调控植物生长发育及对外部环境变换的适应性相关研究,目前已经在主流期刊上发表了13篇文章,其中第一作者(含共同一作)8篇,包括Nature Genetics, Nature Communications, eLife, Genome Biology, Current Opinion in Plant Biology等国际知名期刊。


研究方向:
         课题组将以拟南芥及小麦为研究材料,研究表观遗传调控开花转变,果实发育以及对环境因子变换(光照和温度)的适应性。研究将结合表观遗传组学、转录组学,正向遗传突变体库筛选以及反向基因功能分析,利用高通量测序,遗传,生化,分子,细胞生物学等技术手段来解析染色体调控复合物参与多细胞生物内部发育程序以及外部环境因子诱发的细胞特征重组事件的功能。

Selected Publication:
1.Xiao J, Jin R, Yu X, Shen M, Wagner J, Pai A, Song C, Zhuang M, Kelasfeld S, He CS, Santos AM, Helliwell C, Pruneda-Paz J, Kay S, Lin XW, Cui SJ, Fernandez M, Clarenz O, Goodrich J, Zhang XY, Austin R, Bonasio R, Wagner D. (2017) Cis- and trans-determinants of Polycomb Repressive Complex 2 recruitment in Arabidopsis. Nature Genetics, doi:10.1038/ng.3937 (Nature Genetic news and views highlight, F1000 Prime)
 
2.Xiao J, Xu S*, Li C*, Xu Y, Xing L, Niu Y, Huan Q, Tang Y, Zhao C, Wagner D, Gao C, Chong K. (2014) O-GlcNAc-mediated interaction between VER2 and TaGRP2 elicits TaVRN1 mRNA accumulation during vernalization in winter wheat. Nature Communications 5:4572. (F1000 Prime)
 
3.Wu MF*, Yamaguchi N*, Xiao J*, Bargmann B, Estelle M, Sang Y, Wagner D. (2015) An auxin-regulated chromatin state switch directs organogenesis in Arabidopsis. eLife 4:e09269. (Co-first author, F1000 Prime)
 
4.Xiao J*, Jin R*, Wagner D. (2017) Developmental transitions: integrating environmental cues with hormonal signaling in the chromatin landscape. Genome Biology, 18 (1):88.
 
5.Xiao J, Wagner D. (2015) Polycomb repression in the regulation of growth and development in Arabidopsis. Curr Opin Plant Biol 23C:15-24.
 
6.Xiao J*, Li CH*, Xu SJ, Xing LJ, Xu YY, Chong K. (2015) AtJAC1 Regulates Nuclear Accumulation of GRP7, influencing RNA processing of FLC antisense transcripts and flowering time in Arabidopsis. Plant Physiol 169 (3):2102-2117.
 
7.Xiao J, Lee US, Wagner D. (2016) Tug of war: adding and removing histone lysine methylation in Arabidopsis. Curr Opin Plant Biol 4:41-53.
 
8.Xiao J, Zhang H, Xing LJ, Xu SJ, Liu HH, Chong K, Xu YY. (2013) Requirement of histone acetyltransferases HAM1/2 for epigenetic modification of FLC to regulate flowering in Arabidopsis. J Plant Physiol 170(4):444-451.
 
9.Ma Y, Dai X, Xu Y, Luo W, Zheng X, Zeng D, Pan Y, Lin X, Liu H, Zhang D, Xiao J, Guo X, Xu S, Niu Y, Jin J, Zhang H, Xu X, Li L, Wang W, Qian Q, Ge S, Chong K. (2015) COLD1 Confers Chilling Tolerance in Rice. Cell 160(6):1209-1221. (F1000 Prime, Cover story)
 
10.Bossi F, Fan J, Xiao J, Chandra L, Shen M, Wagner D, Rhee SY. (2017) Systematic discovery of novel eukaryotic transcriptional regulators using non-sequence homology based prediction. BMC Genomics, 18:480 DOI: 10.1186/s12864-017-3853-9
 
11.Liu YJ, Xu YY, Xiao J, Ma QB, Li D, Xue Z, Chong K. (2011) OsDOG, a gibberellin-induced A20/AN1 zinc-finger protein, negatively regulates gibberellin-mediated cell elongation in rice. J Plant Physiol 168(10):1098-1105.
 
12.Li J, Jiang JF, Qian Q, Xu YY, Zhang C, Xiao J, Du C, Luo W, Zou GX, Chen ML, Huang YQ, Feng YQ, Cheng ZK, Yuan M, Chong K. (2011) Mutation of Rice BC12/GDD1, Which Encodes a Kinesin-Like Protein That Binds to a GA Biosynthesis Gene Promoter, Leads to Dwarfism with Impaired Cell Elongation. Plant Cell 23(2):628-640.
 
13.Ma QB, Dai XY, Xu YY, Guo J, Liu YJ, Chen N, Xiao J, Zhang DJ, Xu ZH, Zhang XS* and Chong K*. (2009) Enhanced tolerance to chilling stress in OsMYB3R-2 transgenic rice is mediated by alteration in cell cycle and ectopic expression of stress genes. Plant Physiol 150: 244-256.